HCID 68853364, compound → HCID 68851924, compound

HRID 2112846Notes

Reaction equation

HRID 2112846 reaction equation
Cl.Cl.[Cl:3]C1C=C(C(C2CCCCC2)CN2CCNCC2)C=CC=1.[Cl:24][C:25]1[CH:26]=[C:27]([CH:31]([CH:47]2[CH2:53][CH2:52][CH2:51][CH2:50][CH2:49][CH2:48]2)[C:32]([N:34]2[CH2:39][CH2:38][N:37](C(OC(C)(C)C)=O)[CH2:36][CH2:35]2)=O)[CH:28]=[CH:29][CH:30]=1>>[ClH:3].[ClH:24].[Cl:24][C:25]1[CH:26]=[C:27]([CH:31]([CH:47]2[CH2:53][CH2:52][CH2:51][CH2:50][CH2:49][CH2:48]2)[CH2:32][N:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[CH:28]=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 68853364HCID 68853364, compoundHCID 68856249HCID 68856249, compound

Product 1

HCID 68851924HCID 68851924, compound

Procedure

In an analogous manner to Example 1, step 2, 1-[2-(3-chlorophenyl)-2-cyclohexylethyl]piperazine dihydrochloride was prepared from tert-butyl 4-[(3-chlorophenyl)(cycloheptyl)acetyl]piperazine-1-carboxylate MS (ES) m/z 321.2; HRMS: calcd for C19H29ClN2+H, 321.20975; found (ESI, [M+H]+), 321.2105.

Sources & evidence

ORD record
ord-e805dff45ee94e3ca05b55488b6de6eb
Source dataset
uspto-grants-2009_04
Patent number
US07524846B2

Reaction notes

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