HCID 68854445, compound → HCID 68855659, compound

HRID 2112858Notes

Reaction equation

HRID 2112858 reaction equation
Cl.Cl.[Cl:3]C1C=C([CH:10]([N:23]2[CH2:28][CH2:27][N:26]([CH3:29])[CH2:25][CH2:24]2)[CH2:11][C:12]2([OH:22])[CH:21]3[CH:16]([CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:15][CH2:14][CH2:13]2)C=CC=1.Cl.Cl.[Cl:32][C:33]1[CH:34]=[C:35](C(C2(O)C3C(CCCC3)CCC2)CN2CCNCC2)[CH:36]=[CH:37][CH:38]=1>>[ClH:3].[ClH:32].[Cl:32][C:33]1[CH:38]=[C:37]([CH:11]([C:12]2([OH:22])[CH:21]3[CH:16]([CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:15][CH2:14][CH2:13]2)[CH2:10][N:23]2[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]2)[CH:36]=[CH:35][CH:34]=1

Participants

3

Reactant 2

HCID 68854445HCID 68854445, compoundHCID 86599401HCID 86599401, compound

Product 1

HCID 68855659HCID 68855659, compound

Procedure

In an analogous manner to Example 24 1-[1-(3-chlorophenyl-2-(4-methylpiperazin-1-yl)ethyl]decahydronaphthalen-1-ol dihydrochloride was prepared from 1-[1-(3-chlorophenyl)-2-piperazin-1-ylethyl]decahydronaphthalen-1-ol (see Example 72). MS (ES) m/z 391.3; RMS: calcd for C23H35ClN2O+H, 391.25161; found (ESI, [M+H]+), 391.2528.

Sources & evidence

ORD record
ord-e22f5f4a40544068a78d132c8ca23910
Source dataset
uspto-grants-2009_04
Patent number
US07524846B2

Reaction notes

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