HCID 68852087, compound → HCID 68853180, compound

HRID 2112859Notes

Reaction equation

HRID 2112859 reaction equation
Cl.Cl.[Cl:3][C:4]1C=C(C2(O)CCC(CC)CC2CCN2CCN(C)CC2)C=CC=1.[Cl:28][C:29]1[CH:30]=[C:31]([CH:35]([C:43]2([OH:51])[CH2:48][CH2:47][CH:46]([CH2:49][CH3:50])[CH2:45][CH2:44]2)[CH2:36][N:37]2[CH2:42][CH2:41][NH:40][CH2:39][CH2:38]2)[CH:32]=[CH:33][CH:34]=1>>[ClH:3].[ClH:28].[Cl:28][C:29]1[CH:30]=[C:31]([CH:35]([C:43]2([OH:51])[CH2:48][CH2:47][CH:46]([CH2:49][CH3:50])[CH2:45][CH2:44]2)[CH2:36][N:37]2[CH2:42][CH2:41][N:40]([CH3:4])[CH2:39][CH2:38]2)[CH:32]=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 68852087HCID 68852087, compoundHCID 86599403HCID 86599403, compound

Product 1

HCID 68853180HCID 68853180, compound

Procedure

In an analogous manner to Example 24 1-[1-(3-chlorophenyl)-2-(4-methylpiperazin-1-ylethyl]-4-ethylcyclohexanol dihydrochloride was prepared from 1-[1-(3-chlorophenyl)-2-piperazin-1-ylethyl]-4-ethylcyclohexanol. MS (ES) m/z 365.4; HRMS: calcd for C21H33ClN2O+H, 365.23597; found (ESI, [M+H]+), 365.236.

Sources & evidence

ORD record
ord-a1661e21185f4598813520ce3a26b083
Source dataset
uspto-grants-2009_04
Patent number
US07524846B2

Reaction notes

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