HCID 21187623, compound → HCID 68853888, compound

HRID 2112876Notes

Reaction equation

HRID 2112876 reaction equation
[ClH:1].Cl.C1(O)CCCCC1.[OH:10][C:11]1([CH:17]([C:33]2[CH:38]=[CH:37][C:36]([O:39][CH2:40][CH2:41][C:42]3[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=3)=[CH:35][CH:34]=2)[C:18]([N:20]2[CH2:25][CH2:24][N:23](C(OC(C)(C)C)=O)[CH2:22][CH2:21]2)=O)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1>>[ClH:1].[ClH:1].[C:42]1([CH2:41][CH2:40][O:39][C:36]2[CH:35]=[CH:34][C:33]([CH:17]([C:11]3([OH:10])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]3)[CH2:18][N:20]3[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]3)=[CH:38][CH:37]=2)[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=1

Participants

3

Reactant 2

HCID 21187623HCID 21187623, compoundHCID 68855456HCID 68855456, compound

Product 1

HCID 68853888HCID 68853888, compound

Procedure

In an analogous manner to Example 1, step 2 1-}1-[4-(2-phenylethoxy)phenyl]-2-piperazin-1-ylethyl}cyclohexanol dihydrochloride was prepared from tert-butyl 4-[(1-hydroxycyclohexyl)(4-(2-phenylethoxy)phenyl)acetyl]piperazine-1-carboxylate.

Sources & evidence

ORD record
ord-b275f64fb67041c9bb0ebf4fd8b332a8
Source dataset
uspto-grants-2009_04
Patent number
US07524846B2

Reaction notes

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