反应详情

Ethylamine (0.300 mL, 70% solution in water) and 7-bromo-2-(3-ethyl-ureido)-[1,2,4]triazolo[1,5-a]pyridine-5-carboxylic acid ethyl ester, prepared as in Example 6 (0.251 g, 0.705 mmol), was suspended in ethanol (3.00 mL) and shaken. After 20 hours the reaction was filtered and the filtrate washed with cold ethanol to afford 7-bromo-2-(3-ethyl-ureido)-[1,2,4]triazolo[1,5-a]pyridine-5-carboxylic acid ethylamide MS (APCI+): m/z 356.0 (M+H).

1. filtrationAfter 20 hours the reaction was filtered
2. washthe filtrate washed with cold ethanol