Ethyl isocyanate → HCID 68837724, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of the product of Step 1 (75 mg, 0.23 mmol), ethylisocyanate (92 μL, 1.17 mmol), and dibutyltin diacetate (2 drops) in dry toluene (5 mL) was heated at 125° C. in a microwave reactor for 1 h. After being cooled to room temperature, the precipitated solid was filtered, and washed with chloroform to give 1-ethyl-3-[5-(2-ethyl-thiazol-5-yl)-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-urea as solid. MS m/z 394 (M+H+).

Provenance & Evidence