N-Methylcyclohexylamine → HCID 86618026, compound

Participants

Reaction Steps

A mixture of N-methyl-cyclohexylamine (4 mL) and 5-chloro-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine, which may be produced as in Example 1A, (300 mg, 1.22 mmol) was microwaved at 200° C. for 3 h. On cooling, the product was triturated with toluene/cyclohexane then taken up in CH2Cl2 and washed with aqueous Na2CO3. The organic layer was separated, dried (MgSO4), and concentrated to produce N5-cyclohexyl-N5-methyl-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridine-2,5-diamine. MS m/z 323 (M+H+).

Provenance & Evidence