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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2113023Generated: October 26, 2026

1-Benzyl-1H-pyrazole-4-boronic acid → 2-[4-(1-Benzyl-1H-pyrazol-4-yl)-phenoxymethyl]-thiazole-4-carboxylic acid

https://huagongshe.com/reaction/2113023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-1H-pyrazole-4-boronic acidHCID 3352881—
Reactant2-(4-Iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl esterHCID 57643350—
Product2-[4-(1-Benzyl-1H-pyrazol-4-yl)-phenoxymethyl]-thiazole-4-carboxylic acidHCID 11661112—

Reaction Steps

2-[4-(1-Benzyl-1H-pyrazol-4-yl)-phenoxymethyl]-thiazole-4-carboxylic acid was prepared using general procedure 2 from 2-(4-iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester (of Intermediate 2) and 1-benzyl-1h-pyrazole-4-boronic acid (available from Frontier Scientific, Inc., Logan, Utah). Mass spectrum MH+=392.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524870B2
Source datasetuspto-grants-2009_04
ORD IDord-16a2519dae434393a480a21ce9fbe74c
Source noteuspto-grants-2009_04