HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Carbamoylphenyl)boronic acid → 2-(3'-Carbamoyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Carbamoylphenyl)boronic acid | HCID 2737814 | — |
| Reactant | 2-(4-Iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester | HCID 57643350 | — |
| Product | 2-(3'-Carbamoyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid | HCID 11602817 | — |
Reaction Steps
2-(3′-Carbamoyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid was prepared using general procedure 2 from 2-(4-iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester (of Intermediate 2) and (3-aminocarbonylphenyl)boronic acid (available from Apollo Scientific Ltd., Stockport, UK). Mass spectrum MH+=355.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524870B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-6a79ffaf32354de7b6fbdcd66ddf8350 |
| Source note | uspto-grants-2009_04 |