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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2113028Generated: October 31, 2026

[3-(Hydroxymethyl)phenyl]boronic acid → HCID 11559201, compound

https://huagongshe.com/reaction/2113028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[3-(Hydroxymethyl)phenyl]boronic acidHCID 2734662—
Reactant2-(4-Iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl esterHCID 57643350—
ProductHCID 11559201HCID 11559201—

Reaction Steps

2-(3′-Hydroxymethyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid was prepared using the procedure described above for the preparation of Example 22 from 2-(4-iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester (of Intermediate 2) and 3-(hydroxymethyl)phenylboronic acid (available from Aldrich Chemical Company, Inc., Milwaukee, Wis.). Mass spectrum MH+=342.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524870B2
Source datasetuspto-grants-2009_04
ORD IDord-93be11fa14fe4770a7b0f10f1a732da6
Source noteuspto-grants-2009_04