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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2113031Generated: October 26, 2026

3-(Methoxymethyl)benzeneboronic acid → 2-(3'-Methoxymethyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid

https://huagongshe.com/reaction/2113031

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methoxymethyl)benzeneboronic acidHCID 3825855—
Reactant2-(4-Iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl esterHCID 57643350—
Product2-(3'-Methoxymethyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acidHCID 11494128—

Reaction Steps

2-(3′-Methoxymethyl-biphenyl-4-yloxymethyl)-thiazole-4-carboxylic acid was prepared using general procedure 2 from 2-(4-iodo-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester (of Intermediate 2) and 3-methoxymethylphenylboronic acid (available from Digital Specialty Chemicals, Inc., Dublin, N.H.). Mass spectrum MH+=356.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524870B2
Source datasetuspto-grants-2009_04
ORD IDord-bf29da7a5cb84903b6802a94e61bd10c
Source noteuspto-grants-2009_04