(3-Acetamidophenyl)boronic acid → HCID 11696472, compound

HRID 2113037Notes

Reaction equation

HRID 2113037 reaction equation
C([O:3][C:4](=[O:21])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH2:12][O:13][C:14]2[CH:19]=[CH:18][C:17](I)=[CH:16][CH:15]=2)[CH:7]=1)C.[C:22]([NH:25][C:26]1[CH:27]=[C:28](B(O)O)[CH:29]=[CH:30][CH:31]=1)(=[O:24])[CH3:23]>>[C:22]([NH:25][C:26]1[CH:31]=[C:30]([C:17]2[CH:16]=[CH:15][C:14]([O:13][CH2:12][C:8]3[CH:7]=[C:6]([CH2:5][C:4]([OH:3])=[O:21])[CH:11]=[CH:10][CH:9]=3)=[CH:19][CH:18]=2)[CH:29]=[CH:28][CH:27]=1)(=[O:24])[CH3:23]

Participants

3

Reactant 2

HCID 157274(3-Acetamidophenyl)boronic acidHCID 57643348HCID 57643348, compound2×

Product 1

HCID 11696472HCID 11696472, compound

Procedure

[3-(3′-Acetylamino-biphenyl-4-yloxymethyl)-phenyl]-acetic acid was prepared using general procedure 5 from [3-(4-iodo-phenoxymethyl)-phenyl]-acetic acid ethyl ester (of intermediate 4) and 3-acetamidobenzeneboronic acid (ASDI Incorporated, Newark, Del.). Mass spectrum MH+=376.

Sources & evidence

ORD record
ord-0ddaa0b02e414007951d928982534894
Source dataset
uspto-grants-2009_04
Patent number
US07524870B2

Reaction notes

Loading…