3-Benzylsulfonylamino-6-methyl-1-carboxymethyl-2-pyridinone → HCID 44337735, compound

HRID 2113051Notes

Reaction equation

HRID 2113051 reaction equation
[CH2:1]([S:8]([NH:11][C:12]1[C:13](=[O:23])[N:14]([CH2:19][C:20](O)=[O:21])[C:15]([CH3:18])=[CH:16][CH:17]=1)(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br.Br.[NH2:26][CH2:27][CH:28]1[CH2:37][CH2:36][C:31]2[N:32]=[C:33]([NH2:35])[S:34][C:30]=2[CH2:29]1>>[NH2:35][C:33]1[S:34][C:30]2[CH2:29][CH:28]([CH2:27][NH:26][C:20](=[O:21])[CH2:19][N:14]3[C:15]([CH3:18])=[CH:16][CH:17]=[C:12]([NH:11][S:8]([CH2:1][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=4)(=[O:10])=[O:9])[C:13]3=[O:23])[CH2:37][CH2:36][C:31]=2[N:32]=1

Participants

3

Reactant 2

HCID 154582213-Benzylsulfonylamino-6-methyl-1-carboxymethyl-2-pyridinoneHCID 76852388HCID 76852388, compound

Product 1

HCID 44337735HCID 44337735, compound

Procedure

The title compound was prepared from 2-[3-[(benzylsulfonyl)amino]-6 -methyl-2-oxo-1(2H)-pyridinyl]acetic acid and 6-(aminomethyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-2 -amine dihydrobromide using the procedure of EXAMPLE 1 (STEP 6), and was obtained as a pale solid.

Workup

  1. customwas obtained as a pale solid

Sources & evidence

ORD record
ord-f9c24800e2974050af025d07a2518bf1
Source dataset
uspto-grants-2009_04
Patent number
US07524871B2

Reaction notes

Loading…