HCID 11280704, compound → 2-[3-(2-Chloro-4-fluoro-phenylmethanesulfonylamino)-6-methyl-2-oxo-2H-pyridin-1-yl]-N-(4,5,6,7-tetrahydro-2H-indazol-5-ylmethyl)-acetamide

HRID 2113052Notes

Reaction equation

HRID 2113052 reaction equation
[Cl:1][C:2]1[CH:24]=[C:23]([F:25])[CH:22]=[CH:21][C:3]=1[CH2:4][S:5]([NH:8][C:9]1[C:10](=[O:20])[N:11]([CH2:16][C:17](O)=[O:18])[C:12]([CH3:15])=[CH:13][CH:14]=1)(=[O:7])=[O:6].Cl.Cl.[N:28]1[NH:29][CH:30]=[C:31]2[C:36]=1[CH2:35][CH2:34][CH:33]([CH2:37][NH2:38])[CH2:32]2>>[Cl:1][C:2]1[CH:24]=[C:23]([F:25])[CH:22]=[CH:21][C:3]=1[CH2:4][S:5]([NH:8][C:9]1[C:10](=[O:20])[N:11]([CH2:16][C:17]([NH:38][CH2:37][CH:33]2[CH2:34][CH2:35][C:36]3[C:31](=[CH:30][NH:29][N:28]=3)[CH2:32]2)=[O:18])[C:12]([CH3:15])=[CH:13][CH:14]=1)(=[O:7])=[O:6]

Participants

3

Reactant 2

HCID 11280704HCID 11280704, compoundHCID 178478683HCID 178478683, compound

Product 1

HCID 1784267302-[3-(2-Chloro-4-fluoro-phenylmethanesulfonylamino)-6-methyl-2-oxo-2H-pyridin-1-yl]-N-(4,5,6,7-tetrahydro-2H-indazol-5-ylmethyl)-acetamide

Procedure

The title compound was prepared from 2-[3-{[(2-chloro-4-fluorobenzyl)sulfonyl]amino}-6-methyl-2-oxo-1(2H)pyridinyl]acetic acid and 4,5,6,7-tetrahydro-2H-indazol-5-ylmethanamine dihydrochloride using the procedure of EXAMPLE 1 (STEP 6), and was obtained as a white solid compound.

Workup

  1. customwas obtained as a white solid compound

Sources & evidence

ORD record
ord-37736147f4524985b2bd2357b425c000
Source dataset
uspto-grants-2009_04
Patent number
US07524871B2

Reaction notes

Loading…