[4-(Trifluoromethyl)phenyl]methanesulfonyl chloride → HCID 69037177, compound

HRID 2113054Notes

Reaction equation

HRID 2113054 reaction equation
[NH2:1][C:2]1[C:3](=[O:17])[N:4]([CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[C:5]([CH3:8])=[CH:6][CH:7]=1.[F:18][C:19]([F:32])([F:31])[C:20]1[CH:25]=[CH:24][C:23]([CH2:26][S:27](Cl)(=[O:29])=[O:28])=[CH:22][CH:21]=1>>[CH3:8][C:5]1[N:4]([CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[C:3](=[O:17])[C:2]([NH:1][S:27]([CH2:26][C:23]2[CH:22]=[CH:21][C:20]([C:19]([F:18])([F:31])[F:32])=[CH:25][CH:24]=2)(=[O:29])=[O:28])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 594332[4-(Trifluoromethyl)phenyl]methanesulfonyl chlorideHCID 104901153-Amino-6-methyl-1-(tert-butoxycarbonylmethyl)-2-pyridinone

Product 1

HCID 69037177HCID 69037177, compound

Procedure

The title compound was prepared from tert-butyl 2-[3-amino-6-methyl-2-oxo-1(2H)-pyridinyl]acetate (EXAMPLE 1, STEP 1-3), and [4-(trifluoromethyl)phenyl]methanesulfonyl chloride using the procedure of EXAMPLE 9 (STEP 2), and was obtained as a white solid compound.

Workup

  1. customwas obtained as a white solid compound

Sources & evidence

ORD record
ord-f2cbf70078a24ea98316cabcd2dbe64a
Source dataset
uspto-grants-2009_04
Patent number
US07524871B2

Reaction notes

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