2-[6-methyl-2-oxo-3-({[4 (trifluoromethyl)benzyl]sulfonyl}amino)-1(2H)-pyridinyl]acetic acid → HCID 178426729, compound

HRID 2113055Notes

Reaction equation

HRID 2113055 reaction equation
[CH3:1][C:2]1[N:7]([CH2:8][C:9](O)=[O:10])[C:6](=[O:12])[C:5]([NH:13][S:14]([CH2:17][C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=2)(=[O:16])=[O:15])=[CH:4][CH:3]=1.Cl.Cl.[N:30]1[NH:31][CH:32]=[C:33]2[C:38]=1[CH2:37][CH2:36][CH:35]([CH2:39][NH2:40])[CH2:34]2>>[CH3:1][C:2]1[N:7]([CH2:8][C:9]([NH:40][CH2:39][CH:35]2[CH2:36][CH2:37][C:38]3[C:33](=[CH:32][NH:31][N:30]=3)[CH2:34]2)=[O:10])[C:6](=[O:12])[C:5]([NH:13][S:14]([CH2:17][C:18]2[CH:19]=[CH:20][C:21]([C:24]([F:26])([F:25])[F:27])=[CH:22][CH:23]=2)(=[O:15])=[O:16])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 576433652-[6-methyl-2-oxo-3-({[4 (trifluoromethyl)benzyl]sulfonyl}amino)-1(2H)-pyridinyl]acetic acidHCID 178478683HCID 178478683, compound

Product 1

HCID 178426729HCID 178426729, compound

Procedure

The title compound was prepared from 2-[6-methyl-2-oxo-3-({[4 (trifluoromethyl)benzyl]sulfonyl}amino)-1(2H)-pyridinyl]acetic acid and 4,5,6,7-tetrahydro-2H-indazol-5-y-lmethanamine dihydrochloride using the procedure of EXAMPLE 1 (STEP 6), and was obtained as a white solid compound.

Workup

  1. customwas obtained as a white solid compound

Sources & evidence

ORD record
ord-3ee5676540d74894bc2ecc3e3d1ff047
Source dataset
uspto-grants-2009_04
Patent number
US07524871B2

Reaction notes

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