4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine dihydrobromide → HCID 44339376, compound

HRID 2113058Notes

Reaction equation

HRID 2113058 reaction equation
[CH2:1]([S:5]([NH:8][C:9]1[C:10](=[O:20])[N:11]([CH2:16][C:17]([OH:19])=O)[C:12]([CH3:15])=[CH:13][CH:14]=1)(=[O:7])=[O:6])[CH2:2][CH2:3][CH3:4].Br.Br.[S:23]1[C:27]2[CH2:28][CH:29]([NH2:32])[CH2:30][CH2:31][C:26]=2[N:25]=[C:24]1[NH2:33]>>[NH2:33][C:24]1[S:23][C:27]2[CH2:28][CH:29]([NH:32][C:17](=[O:19])[CH2:16][N:11]3[C:12]([CH3:15])=[CH:13][CH:14]=[C:9]([NH:8][S:5]([CH2:1][CH2:2][CH2:3][CH3:4])(=[O:6])=[O:7])[C:10]3=[O:20])[CH2:30][CH2:31][C:26]=2[N:25]=1

Participants

3

Reactant 2

HCID 136706894,5,6,7-Tetrahydro-benzothiazole-2,6-diamine dihydrobromideHCID 57643354HCID 57643354, compound

Product 1

HCID 44339376HCID 44339376, compound

Procedure

The title compound was prepared from 2-[3-[(butylsulfonyl)amino]-6 -methyl-2-oxo-1(2H)-pyridinyl]acetic acid and 4,5,6,7-tetrahydro-1,3-benzothiazol-2,6-diamine dihydrobromide using the procedure of EXAMPLE 1 (STEP 6). The product was recrystallized from methanol to give a pale brown solid compound.

Workup

  1. customThe product was recrystallized from methanol
  2. customto give a pale brown solid compound

Sources & evidence

ORD record
ord-77f7e442ac514d7d82391547cfc4c211
Source dataset
uspto-grants-2009_04
Patent number
US07524871B2

Reaction notes

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