4-[(4-Bromobenzene)sulfonyl]morpholine → 3-[4-(Morpholine-4-sulfonyl)-phenylethynyl]-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

HRID 211306Notes

Reaction equation

HRID 211306 reaction equation
[Br:26][c:27]1[cH:28][cH:29][c:30]([S:33](=[O:34])(=[O:35])[N:36]2[CH2:37][CH2:38][O:39][CH2:40][CH2:41]2)[cH:31][cH:32]1.[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]>>[C:1](#[C:2][c:27]1[cH:28][cH:29][c:30]([S:33](=[O:34])(=[O:35])[N:36]2[CH2:37][CH2:38][O:39][CH2:40][CH2:41]2)[cH:31][cH:32]1)[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 2531284-[(4-Bromobenzene)sulfonyl]morpholineHCID 715397323-Ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 866080633-[4-(Morpholine-4-sulfonyl)-phenylethynyl]-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

Sources & evidence

ORD record
ord-9120fd34c10e48d4b90f2efcd977def0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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