HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxy-3-(4-methoxyphenyl)benzylazide → 4-Methoxy-3-(4-methoxyphenyl)benzylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxy-3-(4-methoxyphenyl)benzylazide | HCID 22391244 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Methoxy-3-(4-methoxyphenyl)benzylamine | HCID 22391210 | 53.6% |
Reaction Steps
A solution of 4-methoxy-3-(4-methoxyphenyl)benzylazide (0.82 g, 3.07 mmol) in ethanol (50 mL) was hydrogenated under atmospheric pressure for 16 hours. The catalyst was filtered off, the solvent removed under reduced pressure and the crude purified by column chromatography (hexane/ethyl acetate 6/1) to afford 400 mg of title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524873B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-4187fc070e2640e8be743fe232a4c2e7 |
| Source note | uspto-grants-2009_04 |