1-Phenethylamine, (+)- → HCID 60010348, compound

HRID 2113133Notes

Reaction equation

HRID 2113133 reaction equation
[CH2:1]([C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][C:4]=1[C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)[CH3:2].[CH3:19][C@@H:20]([NH2:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:21]1([C@H:20]([NH:27][CH2:7][C:6]2[CH:9]=[CH:10][C:3]([CH2:1][CH3:2])=[C:4]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=3)[CH:5]=2)[CH3:19])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 6431891-Phenethylamine, (+)-HCID 22391258HCID 22391258, compound

Product 1

HCID 60010348HCID 60010348, compound

Procedure

The title compound (0.2 g, white solid as HCl salt) was prepared from 4-ethyl-3-(4-methoxyphenyl)benzaldehyde (0.5 g) and (R)-α-methylbenzylamine (0.265 mL) analogously to Example 66, step 3.

Sources & evidence

ORD record
ord-2cb422b0fd02413d96ed1333779cdbe2
Source dataset
uspto-grants-2009_04
Patent number
US07524873B2

Reaction notes

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