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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2113151Generated: October 29, 2026

2-Ethyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester → 5-[3-(2-Chloro-4-trifluoromethylsulfanyl-phenoxy)-propoxy]-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid

https://huagongshe.com/reaction/2113151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl esterHCID 11160373—
Reactant3-[2-Chloro-4-(trifluoromethylthio)phenoxy]propyl iodideHCID 69050852—
Product5-[3-(2-Chloro-4-trifluoromethylsulfanyl-phenoxy)-propoxy]-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acidHCID 10005230—

Reaction Steps

The title compound was prepared following the general procedure described in Example 1, Step 4 employing the phenol prepared in Example 4, Step 1 and the iodide prepared in Step 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524882B2
Source datasetuspto-grants-2009_04
ORD IDord-8f3f42267d4044ecaceed1e69430e366
Source noteuspto-grants-2009_04