1-[(But-3-en-1-yl)oxy]-2-chloro-4-(trifluoromethoxy)benzene → HCID 57643418, compound

HRID 2113169Notes

Reaction equation

HRID 2113169 reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([O:13][C:14]([F:17])([F:16])[F:15])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][CH2:6][CH:7]=[CH2:8].C[O:19][C:20]([C@:22]1([CH:39]([CH3:41])[CH3:40])[CH2:26][C:25]2[CH:27]=[C:28](OS(C(F)(F)F)(=O)=O)[CH:29]=[CH:30][C:24]=2[O:23]1)=[O:21]>>[Cl:1][C:2]1[CH:12]=[C:11]([O:13][C:14]([F:16])([F:15])[F:17])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][C:28]1[CH:29]=[CH:30][C:24]2[O:23][C@:22]([CH:39]([CH3:40])[CH3:41])([C:20]([OH:21])=[O:19])[CH2:26][C:25]=2[CH:27]=1

Participants

3

Reactant 2

HCID 690508581-[(But-3-en-1-yl)oxy]-2-chloro-4-(trifluoromethoxy)benzeneHCID 86760860HCID 86760860, compound

Product 1

HCID 57643418HCID 57643418, compound

Procedure

The title compound was prepared following the procedure described in Example 16, Step 3, employing the intermediate prepared in Step 1 instead of 5-[(buten-3-yl)oxy]-2-ethyl2,3-dihydro-1-benzofurancarboxylate and the triflate prepared in Step 2 instead of 2-chloro-4(trifluoromethoxy)phenyl trifluoromethanesulfonate.

Sources & evidence

ORD record
ord-db0fc5f407c14ae2a4464ea424a9f787
Source dataset
uspto-grants-2009_04
Patent number
US07524882B2

Reaction notes

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