HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxaloacetic Acid → 4-Hydroxy-4-(3-indolylmethyl)-2-ketoglutaric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxaloacetic Acid | HCID 970 | — |
| Reactant | Pyruvic Acid | HCID 1060 | — |
| Reactant | HCID 19786296 | HCID 19786296 | — |
| Product | 4-Hydroxy-4-(3-indolylmethyl)-2-ketoglutaric acid | HCID 10149460 | — |
Reaction Steps
According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432100B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-7a3e402a4a8b4604936da49f3e7c46ea |
| Source note | uspto-grants-2008_10 |