HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylpyruvic acid → 4-Benzyl-4-hydroxy-2-ketoglutaric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylpyruvic acid | HCID 997 | — |
| Reactant | Pyruvic Acid | HCID 1060 | — |
| Product | 4-Benzyl-4-hydroxy-2-ketoglutaric acid | HCID 10171474 | — |
Reaction Steps
According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432100B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-1fff50506c2a4a5d944f955940948bea |
| Source note | uspto-grants-2008_10 |