HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 66885651, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Fluoro-5-nitrobenzonitrile | HCID 519417 | — |
| Reactant | HCID 69107186 | HCID 69107186 | — |
| Reactant | HCID 178418800 | HCID 178418800 | — |
| Product | HCID 66885651 | HCID 66885651 | — |
Reaction Steps
In analogy to example 5a, 2-fluoro-5-nitro-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 1 h at 20° C. Aqueous workup afforded a 3.6:1 mixture of the title compound and its regioisomer [2-(5-methyl-imidazol-1-yl)-5-nitro-benzonitrile] as a light brown solid (yield: 69%). MS: m/e=229.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432256B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-4650ae235f444ab48e27a5394eea6346 |
| Source note | uspto-grants-2008_10 |