HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroquinazoline → (S)-2-(quinazolin-2-ylamino)methyl-piperidine-1-carboxylic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroquinazoline | HCID 74054 | — |
| Reactant | tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate | HCID 1502020 | — |
| Product | (S)-2-(quinazolin-2-ylamino)methyl-piperidine-1-carboxylic acid tert butyl ester | HCID 86593672 | 55.2% |
Reaction Steps
The title compound (0.6 g) was prepared from (S)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (0.68 g) and 2-chloroquinazoline (0.53 g) according to the method of D30.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432270B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-ecaac523c20142e8b85fac3386d57e46 |
| Source note | uspto-grants-2008_10 |