HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-{[(2S)-piperidin-2-yl]methyl}carbamate → ((S)-1-{1-[4-(4-Fluoro-phenyl)-1-methyl-1H-pyrazol-3-yl]-methanoyl}-piperidin-2-ylmethyl)-carbamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-{[(2S)-piperidin-2-yl]methyl}carbamate | HCID 1501973 | — |
| Reactant | 4-(4-fluorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid | HCID 19768648 | — |
| Product | ((S)-1-{1-[4-(4-Fluoro-phenyl)-1-methyl-1H-pyrazol-3-yl]-methanoyl}-piperidin-2-ylmethyl)-carbamic acid | HCID 67090144 | 110% |
Reaction Steps
The title compound (3.96 g) was prepared from (S)-1-piperidin-2-ylmethyl-carbamic acid tert butyl ester (2.14 g) and 4-(4-fluoro-phenyl)-1-methyl-1H-pyrazol-3-yl carboxylic acid (2.20 g) according to the method of D40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432270B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-8e193f5fdb654ad08510186e1c6e5107 |
| Source note | uspto-grants-2008_10 |