Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 5-phenyl-1,3-oxazole-2-thiol | HCID 12230876 | — |
| Product | 2-Chloro-5-phenyloxazole | HCID 10997626 | — |
Reaction Steps
0.29 g (2.8 mmol) of triethylamine is added to a mixture of 0.5 g (2.8 mmol) of 5-phenyl-3H-oxazole-2-thione (FR 1,450,443) and 2.3 mL of phosphoryl chloride cooled to 0° C. The mixture is heated to 120° C. for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07432269B2 |
|---|
| Source dataset | uspto-grants-2008_10 |
|---|
| ORD ID | ord-13347d6c70a74cdeb138e9255fde5491 |
|---|
| Source note | uspto-grants-2008_10 |
|---|
