Methanol → HCID 44435401, compound

Participants

Reaction Steps

To methyl 3-(3-cyano-6-(2-morpholinoethylamino)-1,7-naphthyridin-4-ylamino)benzoate in tetrahydrofuran (12 mL) was added methyl alcohol (4.5 mL) and lithium hydroxide (1 N, 4.5 mL). After 12 hr the solvents were evaporated and the crude mixture was purified by preparative HPLC to give 3-(3-cyano-6-(2-morpholinoethylamino)-1,7-naphthyridin-4-ylamino)benzoic acid in quantitative yield.

Provenance & Evidence