HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanamine → 3-Chloro-4-phenyl-1-[(pyridin-3-yl)methyl]-1H-pyrrole-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanamine | HCID 31018 | — |
| Reactant | 3-Chloro-4-phenylfuran-2,5-dione | HCID 23447195 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Chloro-4-phenyl-1-[(pyridin-3-yl)methyl]-1H-pyrrole-2,5-dione | HCID 69145172 | — |
Reaction Steps
A solution of 3-chloro-4-phenylfuran-2,5-dione (1.00 mmol, 209 mg) and 3-(aminomethyl)-pyridine (1.00 mmol, 26 mg) in glacial acetic acid (4 mL) was heated in a microwave reactor at 120° C. for two min. After cooling, the solvent was evaporated at reduced pressure. The crude product was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432288B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-015f37b0aa2a452dbb71214733c18070 |
| Source note | uspto-grants-2008_10 |