3-Methoxypropylamine → 3-Chloro-1-(3-methoxypropyl)-4-phenyl-1H-pyrrole-2,5-dione

Participants

Reaction Steps

A solution of 3-chloro-4-phenylfuran-2,5-dione (0.20 mmol, 42 mg) and 1-amino-3-methoxypropane (0.20 mmol, 18 mg) in glacial acetic acid (1 mL) was heated in a microwave reactor at 120° C. for two min. After cooling, the solvent was evaporated at reduced pressure. The crude product was used without purification.

Provenance & Evidence