Methyl iodide → HCID 59811511, compound

Participants

Role	Name	HCID	Charge
Reactant	Methyl iodide	HCID 6328	—
Reactant	3-bromo-7-(2-chloro-4,6-dimethylphenyl)-2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridine	HCID 11360216	—
Reactant	Methyl methylthiosulphonate	HCID 14573333	—
Product	HCID 59811511	HCID 59811511	48%

Reaction Steps

2-Methyl-3-methylsulfanyl-7-(2,4,6-trimethyl-phenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridine (2-20) was prepared according to Example 5 except iodomethane was replaced with methyl methanethiosulfonate (A. I. Meyers and M. A. Sturgess, Tetrahedron Lett. 1988 29:5339) as the electrophile and compound 1-1 was replaced with compound 1-3 to afford 2-20 as a white solid (48% theory; mp=90.3-91.7° C.).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07432283B2
Source dataset	uspto-grants-2008_10
ORD ID	ord-80ea0366453548de85132f6f6ce72852
Source note	uspto-grants-2008_10