7-(2-chloro-4,6-dimethylphenyl)-2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-ylamine → HCID 22136269, compound

HRID 2113798Notes

Reaction equation

HRID 2113798 reaction equation
Cl[C:2]1[CH:7]=C(C)C=C(C)[C:3]=1N1CCCC2=C(N)N(C)N=C12.[CH3:21][N:22]1[C:30]([NH2:31])=[C:29]2[C:24]([N:25]([C:32]3[C:37]([CH3:38])=[CH:36][C:35]([CH3:39])=[CH:34][C:33]=3[CH3:40])[CH2:26][CH2:27][CH2:28]2)=[N:23]1>>[CH2:3]([NH:31][C:30]1[N:22]([CH3:21])[N:23]=[C:24]2[C:29]=1[CH2:28][CH2:27][CH2:26][N:25]2[C:32]1[C:37]([CH3:38])=[CH:36][C:35]([CH3:39])=[CH:34][C:33]=1[CH3:40])[CH2:2][CH3:7]

Participants

3

Reactant 2

HCID 221362787-(2-chloro-4,6-dimethylphenyl)-2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-ylamineHCID 22136293HCID 22136293, compound

Product 1

HCID 22136269HCID 22136269, compound

Procedure

Compound 5-55 was prepared according to the procedure in Example 15, steps 1 and 2, except that in step 1, 7-(2-chloro-4,6-dimethylphenyl)-2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-ylamine (5-45) was replaced with 2-methyl-7-(2,4,6-trimethyl-phenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-ylamine (5-44).

Sources & evidence

ORD record
ord-91f69291153b41c593a5b586a9397fc1
Source dataset
uspto-grants-2008_10
Patent number
US07432283B2

Reaction notes

Loading…