HCID 23093003, compound → HCID 10385109, compound

HRID 2113820Notes

Reaction equation

HRID 2113820 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([O:8][C:9]2[CH:10]=[C:11]([CH:20]=[C:21](C(C)C)[CH:22]=2)[C:12]([NH:14][C:15]2[S:16][CH:17]=[CH:18][N:19]=2)=[O:13])=[N:6][CH:7]=1.[Cu]([C:29]#[N:30])C#N>>[C:29]([C:2]1[CH:3]=[CH:4][C:5]([O:8][C:9]2[CH:10]=[C:11]([CH:20]=[C:21]([O:8][CH:9]([CH3:10])[CH3:22])[CH:22]=2)[C:12]([NH:14][C:15]2[S:16][CH:17]=[CH:18][N:19]=2)=[O:13])=[N:6][CH:7]=1)#[N:30]

Participants

3

Reactant 2

HCID 23093003HCID 23093003, compoundHCID 178418260HCID 178418260, compound

Product 1

HCID 10385109HCID 10385109, compound

Procedure

The reaction between 3-(5-bromo-pyridin-2-yl-oxy)-5-isopropyl-N-thiazol-2-yl-benzamide and copper cyanide may be carried out by a method described in the relevant literature (for example, Comprehensive Organic Transformations, Richard L. et al., VCH Publishers, 1988), a corresponding method, or a combination thereof with an ordinary method.

Sources & evidence

ORD record
ord-4e6364ad63ab42d6863e7b43efaf0314
Source dataset
uspto-grants-2008_10
Patent number
US07432287B2

Reaction notes

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