HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-3-aminopyrazole → 5-(6-ethanesulfonylpyridin-3-yloxy)-3-(2-methoxy-1-methyl-ethoxy)-N-(1-methyl-1H-pyrazol-3-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-3-aminopyrazole | HCID 137254 | — |
| Reactant | (R)-(-)-1-Methoxy-2-propanol | HCID 2733589 | — |
| Reactant | 5-Bromo-2-(ethylsulfonyl)pyridine | HCID 22503164 | — |
| Reactant | Methyl 3-hydroxy-5-(methoxymethoxy)benzoate | HCID 23136427 | — |
| Product | 5-(6-ethanesulfonylpyridin-3-yloxy)-3-(2-methoxy-1-methyl-ethoxy)-N-(1-methyl-1H-pyrazol-3-yl)benzamide | HCID 23093092 | — |
Reaction Steps
The compound of Production Example 138 was obtained as a colorless amorphous substance using 5-hydroxy-3-methoxymethoxybenzoic acid methyl ester, 5-bromo-2-ethanesulfonylpyridine, (2R)-2-hydroxy-1-methoxypropane and 3-amino-1-methyl-1H-pyrazole, by the same method as in Production Example 117, a corresponding method, or a combination thereof with an ordinary method.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432287B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-e9154380647c480b9336139ba8340f84 |
| Source note | uspto-grants-2008_10 |