HRID2113987

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID91621644

未命名化合物

反应SMILES：CS(=O)(=O)c1ccc(NC(=N)N)cc1.O=[N+]([O-])O

HCID178504802

未命名化合物

PRODUCTS

产物

反应SMILES：Cc1nc(C)c(-c2ccnc(Nc3ccc(S(C)(=O)=O)cc3)n2)s1

HCID10383920

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

By condensation of 3-dimethylamino-1-(2,4-dimethyl-thiazol-5-yl)-propenone and N-(4-methanesulfonyl-phenyl)-guanidine nitrate. Yellow solid. Anal. RP-HPLC: tR=16.6 min (0-60% MeCN, purity>97%). 1H-NMR (DMSO-d6) δ: 2.65 (s, 3H, CH3), 2.66 (s, 3H, CH3), 3.15 (s, 3H, CH3), 7.22 (d, 1H, J=5.5 Hz, pyrimidinyl-H), 7.84 (d, 2H, J=9.0 Hz, Ph-H), 8.03 (d, 2H, J=9.0 Hz, Ph-H), 8.61 (d, 1H, J=5.5 Hz, pyrimidinyl-H), 10.23 (sbr, 1H, NH). MS (ESI) m/z 361.17 [M+H]+(C16H16N4O2S2 requires 361.46).