3,4-Dihydro-1-(4-methylphenyl)-4,4-dimethyl-6-acetylnaphthalene → 1-(3,3-Dimethyl-1-p-tolyl-3H-inden-5-yl)-ethanone

Participants

Reaction Steps

Following a procedure similar to that for the preparation of 1-(8,8-dimethyl-5-p-tolyl-7,8-dihydro-naphthalen-2-yl)-ethanone (Compound 5) while using 6-bromo-1,1-dimethyl-3-p-tolyl-1H-indene (Compound 13, 980 mg, 3.14 mmol) as the starting material afforded the title compound (678 mg, 78% yield) as a yellow solid:

Provenance & Evidence