3-Furoic acid → HCID 44593640, compound

Participants

Reaction Steps

N-(4′-{[(Cyclopropylmethyl)amino]carbonyl}-6-methyl-1,1′-biphenyl-3-yl)-3-furamide was prepared from 5′-amino-N-(cyclopropylmethyl)-2′-methyl-1,1′-biphenyl-4-carboxamide and 3-furoic acid using method B. NMR; δH CDCl3 8.10,(1H, s), 7.97,(1H, s), 7.78,(2H, d), 7.64,(1H, dd), 7.47,(1H, m), 7.38,(1H, d), 7.33,(2H, d), 7.24,(1H, d), 6.80,(1H, s), 6.36,(1H, t), 3.32,(2H, m), 2.21,(3H, s), 1.06,(1H, m), 0.57,(2H, m), 0.28,(2m). LCMS: retention time 3.38 min, MH+375.

Provenance & Evidence