HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 59809567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 1-Benzyl-4-piperidone | HCID 19220 | — |
| Reactant | 1H-imidazole-2-carbaldehyde | HCID 24955 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | Tetramethylammonium Triacetoxyborohydride (>90%) | HCID 13696215 | — |
| Reactant | HCID 178419906 | HCID 178419906 | — |
| Product | HCID 59809567 | HCID 59809567 | — |
Reaction Steps
Using an adaptation of the method described in Procedure 7, substituting 4-amino-3-hydroxy-benzoic acid methyl ester for the TFA salt of 10-piperidin-4-yl-3-(1H-tetrazol-5-yl)-10H-phenoxazine, 6a, 1-benzyl-piperidin-4-one for 1H-imidazole-2-carboxaldehyde, and sodium triacetoxyborohydride for tetramethylammonium triacetoxyborohydride, the title compound 4-(1-benzyl-piperidin-4-ylamino)-3-hydroxy-benzoic acid methyl ester, 1d was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432257B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-9facc24cab7449dbbe15b7cc518f8654 |
| Source note | uspto-grants-2008_10 |