HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-piperidone → HCID 59809531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-piperidone | HCID 19220 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | Methyl 3-amino-2-hydroxybenzoate | HCID 12782444 | — |
| Reactant | Tetramethylammonium Triacetoxyborohydride (>90%) | HCID 13696215 | — |
| Reactant | HCID 59809535 | HCID 59809535 | — |
| Product | HCID 59809531 | HCID 59809531 | — |
Reaction Steps
Using an adaptation of the method described in Procedure 3, substituting 3-amino-2-hydroxybenzoic acid methyl ester, 1l for 4-amino-3-(2-bromophenoxy)-benzonitrile, 2a, 1-benzylpiperidin-4-one for 4-oxo-piperidine-1-carboxylic acid tert-butyl ester, and tetramethylammonium triacetoxyborohydride for sodium triacetoxyborohydride, the title compound 3-(1-benzylpiperidin-4-ylamino)-2-hydroxybenzoic acid methyl ester, 2l was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432257B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-52f8aacb05cf451598384a4c7f805d5c |
| Source note | uspto-grants-2008_10 |