HRID2114515

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7244

2-Bromophenol

C6H5BrO

HCID2783399

3-Fluoro-4-nitrobenzonitrile

C7H3FN2O2

HCID22181444

未命名化合物

HCID59809531

未命名化合物

PRODUCTS

产物

HCID59809532

未命名化合物

PROCEDURE

实验过程

Using an adaptation of the method described in Procedure 1, substituting 3-(1-benzylpiperidin-4-ylamino)-2-hydroxybenzoic acid methyl ester, 2l for 2-bromophenol, and N,N-diethyl-4-fluoro-3-nitrobenzamide for 3-fluoro-4-nitrobenzonitrile, the title compound 10-(1-benzylpiperidin-4-yl)-7-diethylcarbamoyl-10H-phenoxazine-4-carboxylic acid methyl ester, 3l was obtained.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-5cbc4e913d48406594e888574c42cda2
来源数据集: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07432257B2
来源说明: uspto-grants-2008_10

反应SMILES

[CH3:1][O:2][C:3](=[O:25])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([NH:10][CH:11]2[CH2:16][CH2:15][N:14]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:13][CH2:12]2)[C:5]=1[OH:24].BrC1C=CC=CC=1O.[CH2:34]([N:36]([CH2:49][CH3:50])[C:37](=[O:48])[C:38]1[CH:43]=[CH:42][C:41](F)=[C:40]([N+]([O-])=O)[CH:39]=1)[CH3:35].FC1C=C(C=CC=1[N+]([O-])=O)C#N>>[CH3:1][O:2][C:3]([C:4]1[C:5]2[O:24][C:42]3[C:41](=[CH:40][CH:39]=[C:38]([C:37](=[O:48])[N:36]([CH2:49][CH3:50])[CH2:34][CH3:35])[CH:43]=3)[N:10]([CH:11]3[CH2:12][CH2:13][N:14]([CH2:17][C:18]4[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=4)[CH2:15][CH2:16]3)[C:6]=2[CH:7]=[CH:8][CH:9]=1)=[O:25]