p-Fluoronitrobenzene → HCID 23104382, 화합물

HRID 2114523노트

반응식

HRID 2114523 반응식
[CH:1]([O:4][CH2:5][CH2:6][CH2:7][NH2:8])([CH3:3])[CH3:2].F[C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1>>[CH:1]([O:4][CH2:5][CH2:6][CH2:7][NH:8][C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1)([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 9590p-FluoronitrobenzeneHCID 761943-Isopropoxypropylamine

생성물 1

HCID 23104382HCID 23104382, 화합물

반응 조건

온도
90 °C

실험 절차

42 ml of 3-isopropoxypropylamine was added to 21 g (0.15 mol) of 1-fluoro-4-nitrobenzene. As the reaction is exothermic, the temperature was maintained at 90° C. by cooling slightly. After 30 minutes, the reaction was complete. The medium was poured onto ice, and an oil appeared. This oil was extracted with ethyl acetate, and the organic phase is washed with water and dried over sodium sulfate. After the oil was evaporated to dryness, 35 g of a yellow oil were obtained.

후처리

  1. temperatureby cooling slightly
  2. additionThe medium was poured onto ice
  3. extractionThis oil was extracted with ethyl acetate
  4. washthe organic phase is washed with water
  5. dry with materialdried over sodium sulfate
  6. customAfter the oil was evaporated to dryness

출처 및 근거

ORD 기록
ord-6abd3b93a92d42418addec87a777177d
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435267B2

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