Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69255225, compound

HRID 2114529Notes

Reaction equation

HRID 2114529 reaction equation
[CH3:1][O:2][CH2:3][CH:4]([OH:16])[CH2:5][NH:6][C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-])=O)=[CH:9][CH:8]=1.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:29].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:29].[ClH:29].[NH2:13][C:10]1[CH:11]=[CH:12][C:7]([NH:6][CH2:5][CH:4]([OH:16])[CH2:3][O:2][CH3:1])=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 56791635HCID 56791635, compound

Product 1

HCID 69255225HCID 69255225, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 1-methoxy-3-[(4-nitrophenyl)amino]propan-2-ol (13) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-3bc7618aa3f64dd083ac5872d5450d97
Source dataset
uspto-grants-2008_10
Patent number
US07435267B2

Reaction notes

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