Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 11185211 | HCID 11185211 | — |
| Reactant | HCID 178418247 | HCID 178418247 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 11175918 | HCID 11175918 | 85% |
Reaction Steps
A mixture of 1-propyl-3-benzyl xanthine (2.82 mmol), CH3CO2Na (2.82 mmol) and acetic acid (15 mL) was heated at 40-50° C. To the solution was added Br2 (2.82 mmol) and the reaction was stirred for further 30 minutes at 45° C. After cooling at room temperature the precipitate was collected by filtration and finally crystallized from EtOH. (White solid. Yield 85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07435740B2 |
|---|
| Source dataset | uspto-grants-2008_10 |
|---|
| ORD ID | ord-9332d3d0287041b0acca4c877756beac |
|---|
| Source note | uspto-grants-2008_10 |
|---|
