1-(2-Bromoethoxy)-4-fluorobenzene → 1-[2-(4-Fluorophenyl)oxyethyl]-4-(4-phenoxyphenyl)piperidine

HRID 211463Notes

Reaction equation

HRID 211463 reaction equation
[F:32][c:33]1[cH:34][cH:35][c:36]([O:39][CH2:40][CH2:41][Br:42])[cH:37][cH:38]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[CH:7][CH2:10][N:11]2[CH2:12][CH2:13][CH:14]([c:17]3[cH:18][cH:19][c:20]([O:23][c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[cH:21][cH:22]3)[CH2:15][CH2:16]2)[cH:8][c:9]1[O:30][CH3:31]>>[CH2:10]([N:11]1[CH2:12][CH2:13][CH:14]([c:17]2[cH:18][cH:19][c:20]([O:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[cH:21][cH:22]2)[CH2:15][CH2:16]1)[CH2:40][O:39][c:36]1[cH:35][cH:34][c:33]([F:32])[cH:38][cH:37]1

Participants

3

Reactant 2

HCID 20641711-(2-Bromoethoxy)-4-fluorobenzeneHCID 539663652-Methoxy-4-[3-[4-(4-phenoxyphenyl)piperidin-1-yl]prop-1-enyl]phenol

Product 1

HCID 187944791-[2-(4-Fluorophenyl)oxyethyl]-4-(4-phenoxyphenyl)piperidine

Sources & evidence

ORD record
ord-258eb268b51648cba7b53da029152141
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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