Hydrogen Bromide → HCID 54676256, compound

Participants

Reaction Steps

A solution of methyl 10-(benzyloxy)-2-(4-fluorobenzyl)-8-methyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrido[3′,4′:4,5]pyrrolo[1,2-a]-pyrazine-4-carboxylat (30 mg, 0.06 mmol) and hydrogen bromide in acetic acid (0.7 mL, 30% solution) in dichloromethane (10 mL) was stirred at room temperature for 6 hr. The reaction mixture was concentrated under vacuum, and the residue subjected to reverse phase HPLC purification. Collection and lyophilization of appropriate fractions provided the title product.

Provenance & Evidence