3-Chlorothiophene-2-carbonyl chloride → HCID 22147918, compound

HRID 2114908Notes

Reaction equation

HRID 2114908 reaction equation
[Cl:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[C:7](Cl)=O.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]([NH:19][NH2:20])=[NH:18])=[CH:13][CH:12]=1>>[Cl:10][C:11]1[CH:12]=[CH:13][C:14]([C:17]2[N:18]=[C:7]([C:3]3[S:4][CH:5]=[CH:6][C:2]=3[Cl:1])[NH:20][N:19]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 27358243-Chlorothiophene-2-carbonyl chlorideHCID 178512501HCID 178512501, compound

Product 1

HCID 22147918HCID 22147918, compound

Procedure

Compounds of this invention with Formula V may be prepared as illustrated by the exemplary reaction in Scheme 4. Reaction of 3-chloro-thiophene-2-carbonyl chloride with 4-chloro-benzenecarboximidic hydrazide produces the product 3-(4-chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-1H-[1,2,4]-triazole.

Workup

  1. customCompounds of this invention with Formula V may be prepared
  2. customas illustrated by the exemplary reaction in Scheme 4

Sources & evidence

ORD record
ord-78a1bd63d7ef4eb2a23ce986bd260283
Source dataset
uspto-grants-2008_10
Patent number
US07435750B2

Reaction notes

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