HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22147930, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-(Trifluoromethyl)benzoyl chloride | HCID 67607 | — |
| Reactant | HCID 22147888 | HCID 22147888 | — |
| Reactant | HCID 23570764 | HCID 23570764 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 22147930 | HCID 22147930 | 93% |
Reaction Steps
N-(3-Chloro-thiophene-2-carbonyl)-N′-(4-trifluoromethylbenzoyl)-hydrazine: A solution of 3-chloro-2-thiophenecarboxylic acid hydrazide (70.4 mg, 0.4 mmol), 4-trifluoromethylbenzoyl chloride (83.6 mg, 0.4 mmol) in pyridine (5 mL) was refluxed for 4 h and then cooled. The solution was diluted by water and the precipitate was collected by filtration, and then dried to yield 129 mg (93%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435750B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-c69a0abcf137412fb401cb677480a0ab |
| Source note | uspto-grants-2008_10 |