Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2114921Generated: October 28, 2026

3-Chlorothiophene-2-carbonyl chloride → 5-[5-(3-Chloro-2-thienyl)-1,2,4-oxadiazol-3-yl]-2-methoxypyridine

https://huagongshe.com/reaction/2114921

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chlorothiophene-2-carbonyl chlorideHCID 2735824—
ReactantHCID 57368824HCID 57368824—
Product5-[5-(3-Chloro-2-thienyl)-1,2,4-oxadiazol-3-yl]-2-methoxypyridineHCID 22147883—

Reaction Steps

The title compound was prepared as in Example 16 from 3-chloro-thiophene-2-carbonyl chloride (0.150 g, 0.828 mmol) and 6-methoxy-pyridine-3-amidoxime (0.138 g, 0.828 mmol) as a white solid (166 mg, 63%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435750B2
Source datasetuspto-grants-2008_10
ORD IDord-96b91005dbf741d6ba50723b6f148428
Source noteuspto-grants-2008_10