4-chloro-N'-hydroxybenzenecarboximidamide → HCID 9968048, compound

HRID 2114931Notes

Reaction equation

HRID 2114931 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6](=[N:8][OH:9])[NH2:7])=[CH:4][CH:3]=1.[CH3:12][C:13]1[S:14][C:15]([C:22]([O-])=O)=[C:16]([C:18]([F:21])([F:20])[F:19])[N:17]=1>>[CH3:12][C:13]1[S:14][C:15]([C:22]2[O:9][N:8]=[C:6]([C:5]3[CH:10]=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=3)[N:7]=2)=[C:16]([C:18]([F:21])([F:19])[F:20])[N:17]=1

Participants

3

Reactant 2

HCID 2246504-chloro-N'-hydroxybenzenecarboximidamideHCID 7062340HCID 7062340, compound

Product 1

HCID 9968048HCID 9968048, compound

Procedure

The title compound was prepared from 4-chlorobenzamidoxime and 2-methyl-4-trifluoromethyl-thiazole-5-carboxylate similar to Example 16 as a light orange solid. 1H NMR (CDCl3): 8.08 (dd, J=8.52, 2.20 Hz, 1H), 7.50 (dd, J=8.51, 2.13 Hz, 1H), 2.85 (s, 3H).

Sources & evidence

ORD record
ord-c4761d09744f4eb98bcaf0085caa5664
Source dataset
uspto-grants-2008_10
Patent number
US07435750B2

Reaction notes

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